Research: Chemistry disrupts metabolic metabolism in children
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Potentially toxic chemicals found in everyday items, including fast food wrappers, cosmetics and carpeting, alter the hormonal and metabolic processes that occur in a child as they grow and develop, according to a new study.
The researchers analyzed samples for study in young children, adolescents, and young adults, all of whom had a mixture of various synthetic compounds called perfluoroalkyl and polyfluoroalkyl substances — or PFAS — in their blood, including PFOS, PFOA, PFHxS, PFNA, PFHpS, and PFDA.
The US Environmental Protection Agency recently announced stringent controls on the levels of some of these chemicals in the country’s drinking water.
“Exposure to the PFAS combination not only disrupted lipid and amino acid metabolism, but also altered thyroid hormone function in children,” said lead author Jesse Goodrich, assistant professor of population and public health at the University of Southern California Keck School of Medicine. .
The Mayo Clinic noted, that for the proper development of children, the thyroid produces two key hormones that play a role in blood pressure control and how the body makes and uses proteins, fats, and carbohydrates. Chemicals, on the other hand, “affect every cell in the body.”
“This study provides an in-depth analysis of how PFAS exposure affects not only human hormone levels, but also various metabolic pathways,” said David Andrews, senior scientist at the Environmental Working Group, the advocacy group that created the national map. sites contaminated with PFAS.
“Changes in these metabolic markers could be indicative of a number of different future health outcomes for children, such as increased susceptibility to obesity, insulin resistance, increased risk of fatty liver and possibly cancer,” Andrews said.
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